SPRING HEALTH

April Koh was studying computational neuroscience at Yale when she encountered research on precision medicine for depression — the idea that you could use data to predict which patients would respond to therapy versus medication versus a combination. The existing system was essentially trial and error: try an antidepressant for six weeks, and if it doesn't work, try another one.

Meanwhile, patients suffer. Koh co-founded Spring Health in 2016 with Adam Chekroud, a Yale neuroscience PhD, to build a platform that uses machine learning to match employees to the right mental health treatment on the first try.

They started by publishing peer-reviewed research showing their algorithms could predict treatment response better than chance, then turned that research into a product that employers would pay for.

B2B employer benefit — similar model to Lyra Health but with a sharper focus on precision matching. Companies pay Spring Health a per-employee-per-month fee.

Employees take an initial assessment and Spring Health's algorithm recommends a care pathway: therapy, medication management, coaching, digital self-care, or a combination. The key differentiator is the precision — the algorithm claims to reduce treatment time by 50% by getting the right match first instead of cycling through options.

Spring Health also provides a therapist network, psychiatric services, and crisis support. Revenue scales with employer contracts and employee utilization.

Precision mental health platform — ML-driven assessment that predicts optimal treatment pathway for each individual. Therapist matching engine connecting employees to the right provider by specialty, approach, and predicted fit.

Spring Health Moments — bite-sized digital exercises based on CBT for mild symptoms. Medication management through in-house psychiatric providers.

Manager and HR tools for supporting teams without violating privacy. Work-life coaching for non-clinical needs like stress and work-life balance.

Family support extending benefits to dependents. Crisis support including 24/7 access for emergencies.

Enterprise sales to large employers, competing directly with Lyra Health, Headspace Health, and traditional EAP providers. Spring Health leads with outcomes data — publishing research showing faster recovery times and higher clinical improvement rates than industry benchmarks.

Celebrity advisor Apolo Ohno and high-profile board members gave early credibility. Series C at $2.5 billion valuation generated press coverage that opened doors.

International expansion to serve global workforces. Strategic investment from Kinnevik gave European distribution relationships.

Partnership with health plans to offer Spring Health as the behavioral health component within existing benefits.

Direct competition with Lyra Health, which is larger and better-funded. The employer mental health benefit space is crowded and increasingly commoditized — every startup claims better outcomes and faster ROI.

Therapist supply is the binding constraint across the entire industry. Proving that ML-driven matching actually produces better outcomes than simply having a good therapist network is a difficult clinical claim to substantiate at scale.

Employee engagement is everything — if employees don't take the initial assessment, the precision matching engine can't work. And the macro headwind: employer benefits budgets are under pressure, and mental health benefits are easier to cut than medical benefits when money gets tight.

Investors include Tiger Global Management, Kinnevik, Northzone, William K. Warren Foundation, and Able Partners.

Series C in 2022 valued the company at $2.5 billion.